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Human Embryonic Stem cells improve monkeys with Parkinson’s

Tuesday, February 21, 2012

Laaska News Feb. 21, 2012

A group of Japanese scientists has succeeded in improving the conditions of monkeys with Parkinson’s disease after transplants of nerve cells generated from human Embryonic stem cells, or ES cells.

This is the first success in using ES cells to improve the condition of primates.

Associate Professor Jun Takahashi and his research team at the Institute for Frontier Medical Sciences of Kyoto University conducted the experiment.

They transplanted dopaminergic neurons generated from human ES cells in the brain of 4 monkeys suffering from Parkinson’s disease.

Three months later, all 4 monkeys, who had been unable to move, began to walk. They also stopped trembling and other symptoms of Parkinson’s disease were also eased.

The research group also confirmed that the monkeys’ cells implanted with the human ES cells have not been transformed into a tumor.

The researchers say they hope to carry out clinical research in 4 or 6 years time, after enhancing the safety of the treatment methods.

They say this success has marked a step forward toward practical application to human treatment.



Laaska News.